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Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer. It starts in connective tissue cells in the middle layer of the skin (dermis).
Dermatofibrosarcoma protuberans might look like a pimple or feel like a firm patch of skin at first. As it grows, lumps of tissue (protuberans) may form near the surface of the skin. This skin cancer often forms on the arms, legs and trunk.
Dermatofibrosarcoma protuberans grows slowly and rarely spreads beyond the skin.
Symptoms of dermatofibrosarcoma protuberans include:
The lumps typically appear on the arms, legs or trunk. They rarely form on the head or neck.
Make an appointment with a doctor or other healthcare professional if you have ongoing symptoms that worry you.
The cause of dermatofibrosarcoma protuberans often isn't known.
This skin cancer happens when cells in the skin develop changes. The changes happen in the cells' chromosomes. Chromosomes are threadlike structures inside cells that contain DNA and proteins. The changes in the chromosomes cause the cells to make many more cells quickly. The cancer cells form a growth that starts underneath the skin and may push up to create a lump over time. Other lumps may appear as well.
Risk factors for dermatofibrosarcoma protuberans include:
There is no way to prevent dermatofibrosarcoma protuberans.
Tests and procedures used to diagnose dermatofibrosarcoma protuberans include:
Dermatofibrosarcoma protuberans treatment typically involves surgery to remove the cancer. Other treatments may be used to kill cancer cells that might remain after surgery.
Treatment options may include:
Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you. If your health professional believes you may have skin cancer, that person may refer you to a specialist. Often this is a doctor who specializes in treating skin conditions, called a dermatologist.
Appointments can be short, and being prepared can help. Here's some information that may help you get ready.
When you make the appointment, ask if there's anything you need to do in advance, such as fasting before having a specific test. Make a list of:
Take a family member or friend along, if possible, to help you remember the information you're given.
For dermatofibrosarcoma protuberans, some basic questions to ask your health professional include:
Don't hesitate to ask other questions.
Your healthcare professional is likely to ask you several questions, such as: