Health Information Library

All the content of the library is provided from Mayo Clinic in English.
As a member of the Mayo Clinic Care Network, RSPP has special access to Mayo Clinic knowledge and resources.

< Back

Blisters: First aid


If a blister isn't too painful, try to keep it intact. Unbroken skin over a blister may provide a natural barrier to bacteria and decreases the risk of infection. Cover it with a bandage or moleskin. Cut a piece of moleskin into a doughnut shape and place the pad so that it encircles and protects the blister. Then cover the blister and moleskin with gauze.

Seek medical care if the blister looks infected. If you have diabetes or poor circulation, call your doctor before treating the blister yourself.

How to drain a blister

To relieve blister-related pain, drain the fluid while leaving the overlying skin intact. Here's how:

  • Wash your hands and the blister with soap and warm water.
  • Swab the blister with iodine.
  • Clean a sharp needle with rubbing alcohol.
  • Use the needle to prick the blister in several spots near the edge. Let the fluid drain, but leave the overlying skin in place.
  • Apply an ointment such as petroleum jelly to the blister and cover it with a nonstick gauze bandage. If a rash appears, stop using the ointment.
  • Follow-up care. Check the area every day for infection. After several days, use a tweezers and scissors sterilized with rubbing alcohol to cut away the dead skin. Apply more ointment and a bandage.

Blister prevention

To prevent friction blisters on your feet, wear shoes that fit well. It also helps to use moisture-wicking socks. Try the various socks, shoes and insoles that are designed specifically to help reduce blistering. You might also try attaching moleskin to the inside of your shoes where it might rub. Or you can dust the inside of your socks with foot powder. Gloves help prevent blisters on your hands.

Content Last Updated: 06-Jan-2024
© 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Terms of Use.